Targeting the angiotensin II type 2 receptor (AT2R) in colorectal liver metastases
1980 corvette tail lights Abstract Background Blockade of the angiotensin (ANG) II type 1 receptor (AT1R) inhibits tumour growth in several cancers, including colorectal cancer (CRC) liver metastases.While AT1R blockade has been extensively studied, the potential of targeting the antagonistically acting AT2R in cancer has not been investigated.This